How Nurse Practitioner (NP)s in Missouri get paid in 2026 — median, range, experience tiers, metro breakdown, and a comparison against national pay.
Pay tiers reflect typical Missouri compensation across career stages. Specialized employers may pay above these ranges.
| Experience | Median 2026 | 25th % | 75th % |
|---|---|---|---|
| Entry (0–1 yr) | $87,900 | $66,800 | $114,300 |
| Junior (2–4 yrs) | $109,200 | $83,000 | $142,000 |
| Mid-Level (5–9 yrs) | $125,600 | $95,500 | $163,300 |
| Senior (10–14 yrs) | $150,700 | $114,600 | $195,900 |
| Veteran (15+ yrs) | $170,800 | $129,800 | $222,000 |
Top occupations by median pay in Missouri — useful context if you're weighing a career switch.
→ See full ranking of top 25 highest-paying jobs in Missouri
If you'd consider relocating, here's how regional and comparable markets pay for the same job.
The average Nurse Practitioner (NP) salary in Missouri is $125,600 per year as of 2026, based on projections from BLS Occupational Employment Statistics. The 25th percentile sits at $95,500 and the 75th at $163,300.
Pay-wise, Missouri sits -11% below the national Nurse Practitioner (NP) median ($141,100). Wages run below the national median, but cost of living is often correspondingly lower; net purchasing power may be similar to higher-paying states.
Senior Nurse Practitioner (NP)s (10–14 years of experience) in Missouri earn around $150,700 per year on average. Veterans with 15+ years can reach $170,800 or more, especially at the 75th percentile and above.
Among all 51 jurisdictions (50 states + DC), Missouri ranks 35th for Nurse Practitioner (NP) pay. The highest-paying state pays around $204,600 on average.
The median is a benchmark, not a verdict. Your exact market value depends on your experience and education — plus your specific employer's pay band. Run the free calculator for a personalized number.
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